Terminal restriction fragment length polymorphisms...

Anaerobic bacteria in cystic fibrosis: pathogenic or harmless commensal? Application of molecular non-culture-based methods developed to characterize the bacterial communities, such as 16S rRNA gene profiling

Terminal restriction fragment length polymorphisms (T-PDRF) or pirosekvenirovaniya it possible to obtain new information in the

Microbiology of cystic fibrosis ( CF) lung disease. Studies have shown that instead dominated by one or a small number of microorganisms, light filled CF

on a much more diverse polymicrobial community, including the optional anaerobic bacteria. Analysis of CF respiratory samples >> << severe anoxic culture and culture independent molecular methods have shown that anaerobic species can be re

isolated, suggesting that their strattera presence is permanent, not transient, and are present in figures can be compared to you

typical aerobic bacterial pathogens. Anaerobes present often represent the ones that usually colonize the oropharynx. A relative number of anaerobes in

samples and differences in the anaerobic species between mouthwash samples and sputum samples, suggests that

they are not verbal pollution, but they really come from the lower respiratory tract. These anaerobes are present in the lungs in CF, perhaps, not surprising. There is a gradient of oxygen in the respiratory tract CF,

with regions of hypoxia in the mucous plugs. In chronic infection, the main agent of CF,

aeruginosa adapt to these conditions, increasing alginate production, formation of biofilms and the transition to anaerobic metabolism. Regions of anoxia in warm, moist, nutrient-rich environment, combined with defective mucociliary clearance mechanism could allow obligate anaerobic bacteria colonize or infect the lungs in CF. Although there is convincing evidence that obligate anaerobic species.